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In the ever-evolving landscape of cancer treatment, Microsatellite Instability (MSI) has emerged as a pivotal factor, particularly in the context of immunotherapy. MSI, a form of genetic hypermutability, occurs due to defects in the DNA mismatch repair (MMR) system. Understanding MSI’s role and its implications in immunotherapy not only offers insights into cancer biology but …

MSI Instability: A Key Player in the Realm of Immunotherapy Read More »

Cancer, a formidable adversary in the realm of human health, has long evaded the grasp of definitive cure. However, the advent of immunotherapy, particularly checkpoint inhibitors, has revolutionized the approach to cancer treatment. This blog delves into the intricate world of checkpoints, their role in immunotherapy, the various types available, the drugs targeting these checkpoints, …

Checkpoints and Their Role in Immunotherapy: Navigating the Landscape of Cancer Treatment Read More »

In the dynamic world of cancer research, the concept of Tumor Mutational Burden (TMB) has emerged as a crucial biomarker in the realm of immunotherapy. TMB refers to the number of mutations within a tumor genome. Understanding its role in the effectiveness of immunotherapy treatments is reshaping how oncologists approach cancer treatment, offering a more …

Tumor Mutational Burden: A New Frontier in Immunotherapy Read More »